For women who are breastfeeding: Acetaminophen is passed in small amounts in breast milk. Hydrocodone also passes into breast milk and may result in excessive tiredness and slowed breathing in a child who is breastfed. Breastfeeding while taking this medication may come with risks.
For seniors: Older adults may have decreased kidney, liver, and heart function. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages.
Always speak with your doctor or pharmacist about dosages that are right for you. Acetaminophen-hydrocodone is used for short- or long-term treatment. For this drug to work well, a certain amount needs to be in your body at all times. This could result in dangerous side effects. If you take too much: If you take too much, you can overdose on this medication.
You may experience:. But if your symptoms are severe, call or go to the nearest emergency room right away. A prescription for this medication is not refillable. You or your pharmacy will have to contact your doctor for a new prescription if you need this medication refilled. Your doctor may do certain tests to check whether you have severe liver or kidney disease. These tests will check your:. There are other drugs available to treat your condition.
Some may be more suitable for you than others. Talk to your doctor about other drug options that may work for you. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication.
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
People can take acetaminophen and ibuprofen together. Learn more about the correct dosages and side effects, and when a person should see a doctor. People have used natural pain relief methods for centuries.
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The main difference between most of these medications is the amounts of hydrocodone and acetaminophen. They're all prescribed to treat moderate to severe pain. All versions of Norco come as a tablet. Combination drugs with less than 15 milligrams of hydrocodone per dose unit like Norco are classified as Schedule II substances, meaning they are considered to have a high potential for misuse, with use potentially leading to severe psychological or physical dependence.
Norco is taken orally in tablet form and the drug must pass through the digestive system before it begins to take effect. The acetaminophen in Norco tends to be rapidly absorbed in the gastrointestinal tract and begins to take effect within 10 to 30 minutes of ingestion.
The hydrocodone component of Norco is slower-acting but begins to relieve pain about 30 to 60 minutes after ingestion. When talking about how long a particular medication remains active in the body it helps to understand the concept of half-life. Half-life refers to the amount of time it takes for half of the dose of a particular drug to be eliminated from the body.
For Norco, of course, it's necessary to consider both the half-life of hydrocodone and the half-life of acetaminophen. The half-life of hydrocodone is about four hours. After five or six half-lives, the drug has been mostly eliminated from your system. However, it is important to note that even at this point, hydrocodone can be detected in the urine for up to three days. This means that if you take a urine drug screen after being on Norco, it is likely to test positive for opiates even if your last dose was days earlier.
Hydrocodone is metabolized by the liver into its major metabolites hydromorphone and dihydrocodeine. The acetaminophen in Norco has a half-life in the blood of an hour and 15 minutes to three hours. Acetaminophen is rapidly absorbed in the gastrointestinal tract, eliminated primarily by the liver, and later excreted by the kidney as metabolites. Most acetaminophen has passed out of the body through the urine after 24 hours. Because urine tests are sometimes susceptible to false positives, a positive test for opioid use on a standard drug screen may be followed up with a blood test to confirm the results.
Norco may be detectable by a blood test for up to 24 hours after ingesting the last dose. While blood tests provide greater accuracy, they are also much more invasive and costly. Because of this, this type of testing is not often used in occupational settings but is more common in forensic and legal contexts.
Hair testing can detect Norco metabolites in hair follicle samples for up to 90 days after the last dose. It may be used in instances where employers or law enforcement are looking at past drug use or misuse. Due to its hydrocodone contents, Norco may be detectable in saliva for up to three days after ingestion. While saliva testing has some advantages, including being fairly easy to administer and non-invasive, the small specimen size can present testing challenges.
Norco may be detectable in the urine for up to three days after taking a dose. If you have been taking Norco, you may test positive for opioids on a standard immunoassay urine drug screening. You should inform the lab that you have been taking this prescription medication for pain management so that they are able to interpret your results accurately.
A number of different individual factors can play a role in how long Norco remains detectable in the body. Such factors include:.
It's important to know how long a medication like Norco stays in the body since substances such as alcohol as well as other medications can lead to potentially dangerous interactions with either hydrocodone or acetaminophen.
For example, if you were to take significant amounts of Tylenol or an OTC cold or cough medication containing acetaminophen before Norco has cleared from your system, you potentially could wind up with an overdose of acetaminophen in your body—a situation that has been found to lead to severe liver damage, according to the Food and Drug Administration FDA.
Understanding how long Norco remains active in the body and when it will clear can help you and your doctor time your doses so that you get the most benefit without the risk of side effects.
The only surefire way to get Norco out of your system is to stop taking the drug and give your body time to eliminate it; exercising or drinking a lot of water will not flush the drug out of your system. To avoid unpleasant withdrawal symptoms, work with your doctor to taper off the medication slowly. Knowing how long Norco remains in the system also can help prevent an accidental overdose caused by taking too much of the medication too soon. The following are some of the signs and symptoms of a Norco overdose:.
If you or someone you're caring for is taking Norco and experiences any of these symptoms, call In the event the overdose has caused loss of consciousness, first responders can administer a drug called Narcan naloxone to counteract the effects of the hydrocodone. Because hydrocodone is an opiate narcotic, it brings a risk of dangerous interactions with a number of different substances, including alcohol and other drugs.
Drinking while taking Norco can lead to serious side effects caused by either the combination of alcohol with hydrocodone or the combination of alcohol with acetaminophen, according to the National Institute on Alcohol Abuse and Alcoholism. Liver damage caused by acetaminophen is a particularly serious problem. That may seem odd since Tylenol and other over-the-counter medications containing acetaminophen are so accessible, but that's part of the problem.
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